Phenolphthalein

Phenolphthalein is white to light yellow crystal powder. This product is a commonly used acid indicator with the range of color change between pH 8.2 (colorless) to 10.0 (red). Phenolphthalein is also a drug, can be used as a laxative, acting on the colon for the treatment of constipation. Used as an acid-base indicator; as irritant laxative for the treatment of constipation.

Identification:

Product name: Phenolphthalein

CAS:77-09-8

Synonyms: 2-[Bis(4-hydroxyphenyl)methyl]benzoic acid; 3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone; 3,3-Bis(4-hydroxyphenyl)phthalide

Molecular formula:C20H14O4

Molecular weight:318.33

EINECS:201-004-7

Properties：

Melting point :258-263 °C

Boiling point :417.49°C (rough estimate)

Density :1.299

Refractive index :1.5400 (estimate)

Flash point : 24 °C

Solubility : Soluble in alcohol. Slightly soluble in ether. Slightly soluble in dimethyl sulfoxide and insoluble in benzene or hexane.

Form : Solid

Pka: 9.4(at 25℃)

Colour Index :764

Color :White to yellow-white

PH range :8.0(colorless)-10(Red)

PH : 7.8～10.0

Water solubility :<0.1 g/100 mL

λmax:552nm, 553nm, 374nm, 205nm, 229nm, 276nm

Specification:

Characteristics :A white or almost white powder, practically insoluble in water, soluble in alcohol.

Melting Point :It melts at about 260℃

Identification :A:Positive B:Positive

Appearance of solution :The solution is clear and not more intensely coloured than reference solution Y7

Related substances :Less than 0.5%

Heavy metals :Not more than0.001%

Acidity or alkalinity :Complies

Chlorides :Not more than 0.01%

Sulphates :Not more than 0.02%

Loss on drying :Not more than 0.5%

Sulphated ash :Not more than 0.1%

Assay :98.0%-101.0%(C20H14O4)

Product Package:

Fiber drum, net weight 25kg per drum,or according to the requirements of the customers.

Product Storage: 

Put in a sealed, dry and ventilated place, Guard Against Fire.

Application:

Pharmacological application: Mainly acts on the colon. After oral administration, it slowly decomposes under the action of small intestinal alkaline intestinal juice to form soluble sodium salt, thereby stimulating the inner lining of the intestinal wall, directly acting on the intestinal smooth muscle, increasing intestinal peristalsis and inhibiting at the same time. The absorption of water in the intestine causes water and electrolyte to accumulate in the colon, causing a laxative effect. Its effect is moderate, rarely causing intestinal cramps. For the treatment of habitual intractable constipation.

Some photos of shipment: